One of the most prominent advantages of wood over MDF is that it's a stronger and more durable material. The natural grain in wood remains when finished with stains or paint and adds texture to your kitchen cabinets. Scratches or dents in wood cabinets can easily be repaired with sandpaper and a new coat of stain.
A disadvantage of wood is that it expands and contracts with natural temperature fluctuations. This is a common issue with painted wood cabinets, as the paint can bubble or crack.
MDF stands up better to changes in heat and humidity, it also has a smooth, grainless surface which makes it the better option for painted cabinets. The material is further resistant to pests and bugs because of the resins that hold the wood fibres together.
The biggest advantage of MDF kitchen cabinets is that they come at a considerably lower price tag.
Because the fibreboards are grainless and will absorb fluids, you can't stain them. MDFl is very susceptible to water and will swell and distort if not sealed properly. Dents or scratches in MDF panels can't be fixed and the flaws will remain unless you replace the damaged cabinet door. The particles MDF is made off will also not hold screws as well as a solid wood panel.